The most common adverse reaction in patients aged 12 years and older that occurred more frequently on ZYRTEC (cetirizine) than placebo was . The incidence of somnolence associated with ZYRTEC (cetirizine) was dose related, 6% in placebo, 11% at 5 mg and 14% at 10 mg. Discontinuations due to somnolence for ZYRTEC (cetirizine) were uncommon (1.0% on ZYRTEC (cetirizine) vs. 0.6% on placebo). and also appeared to be treatment-related adverse reactions. There were no differences by age, race, gender or by body weight with regard to the incidence of adverse reactions.
Most adverse reactions reported during therapy with ZYRTEC (cetirizine) were mild or moderate. In placebo-controlled trials, the incidence of discontinuations due to adverse reactions in patients receiving ZYRTEC (cetirizine) 5 or 10 mg was not significantly different from placebo (2.9% vs. 2.4%, respectively).
OTC ZYRTEC® is covered by most FSAs and HSAs. Check with your benefits administrator for more information about coverage and how to use your FSA or HSA dollars to pay for OTC ZYRTEC® products.